Endocrine Abstracts

Over the last decades, studies using pharmacological approaches and transgenic mouse models have defined the major roles of bile acids as signaling molecules. Bile acids control many physiological functions such as lipid homeostasis, glucose, and energy metabolisms. In the last years, bile acids have been demonstrated to control male reproductive function. Here, we will highlight the impacts of bile acids on testicular physiology fo...

Male fertility is controlled by complex interactions among the hypothalamus, pituitary, and testis. The major functions of the testis include production of spermatozoa (male gametes) and synthesis of testosterone. Testosterone is produced by the testicular Leydig cells and is responsible for the development of gonad, the attainment of puberty, and the maintenance of secondary sexual characteristics. It is also involved in the maintenance of of spermatogenesis and thus ensuring...

Male fertility is controlled by complex interactions between hypothalamus, pituitary, and testis. The major functions of the testis include production of spermatozoa and synthesis of hormones. Testosterone is produced by the testicular Leydig cells and ensures male fertility. Testosterone is involved in the development of gonad, the attainment of puberty, the maintenance of secondary sexual characteristics as well as in spermatogenesis process. Many studies have highlighted th...